Taxometric analyses and predictive accuracy of callous-unemotional traits regarding quality of life and behavior problems in non-conduct disorder diagnoses

PSYCHIATRY RESEARCH

卷:253

Article

Herpers, Pierre C. M.^1,2  Klip, Helen¹  Rommelse, Nanda N. J.^1,2  Taylor, Mark J.³  Greven, Corina U.^4,5  Buitelaar, Jan K.⁴ 

[1] Univ Ctr, Karakter Child & Adolescent Psychiat, Reinier Postlaan 12, NL-6525 GC Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, Donders Inst Brain Cognit & Behav, Dept Psychiat, Kapittelweg 29, NL-6525 EN Nijmegen, Netherlands

[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Nobels Vag 12A, S-17177 Stockholm, Sweden

[4] Radboud Univ Nijmegen, Med Ctr, Donders Inst Brain Cognit & Behav, Dept Cognit Neurosci, Kapittelweg 29, NL-6525 EN Nijmegen, Netherlands

[5] Kings Coll London, Social Genet & Dev Psychiat Ctr, Inst Psychiat Psychol & Neurosci, MRC, Crespigny Pk, London SE5 8AF, England

关键词: Callous-unemotional traits;    ADHD;    Autism;    Oppositional-defiant disorder;    Conduct disorder;    Anxiety/mood disorders;    Taxon;    Quality of life;   

DOI  :  10.1016/j.psychres.2017.04.004

来源: Elsevier

【 摘 要 】

Callous-unemotional (CU) traits have mainly been studied in relation to conduct disorder (CD), but can also occur in other disorder groups. However, it is unclear whether there is a clinically relevant cut-off value of levels of CU traits in predicting reduced quality of life (QoL) and clinical symptoms, and whether CU traits better fit a categorical (taxonic) or dimensional model. Parents of 979 youths referred to a child and adolescent psychiatric clinic rated their child's CU traits on the Inventory of Callous-Unemotional traits (ICU), QoL on the Kidscreen-27, and clinical symptoms on the Child Behavior Checklist. Experienced clinicians conferred DSM-IV-TR diagnoses of ADHD, ASD, anxiety/mood disorders and DBD-NOS/ODD. The ICU was also used to score the DSM-5 specifier 'with limited prosocial emotions' (LPE) of Conduct Disorder. Receiver operating characteristic (ROC) analyses revealed that the predictive accuracy of the ICU and LPE regarding QoL and clinical symptoms was poor to fair, and similar across diagnoses. A clinical cut-off point could not be defined. Taxometric analyses suggested that callous-unemotional traits on the ICU best reflect a dimension rather than taxon. More research is needed on the impact of CU traits on the functional adaptation, course, and response to treatment of non-CD conditions.

【 授权许可】

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