Validity and reliability of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) in Japanese patients with bipolar disorder

PSYCHIATRY RESEARCH

卷:254

Article

Toyoshima, Kuniyoshi¹  Fujii, Yutaka²  Mitsui, Nobuyuki¹  Kako, Yuki¹  Asakura, Satoshi²  Martinez-Aran, Anabel³  Vieta, Eduard³  Kusumi, Ichiro¹ 

[1] Hokkaido Univ, Grad Sch Med, Dept Psychiat, Sapporo, Hokkaido, Japan

[2] Hokkaido Univ, Hlth Care Ctr, Sapporo, Hokkaido, Japan

[3] Univ Barcelona, Inst Neurosci, Hosp Clin, Bipolar Disorders Program,IDIBAPS,CIBERSAM, Villarroel 170, Barcelona 08036, Catalonia, Spain

关键词: Subjective cognitive impairment;    Japan;    Neuropsychological tests;    Cognition;    COBRA;    Bipolar disorder;   

DOI  :  10.1016/j.psychres.2017.04.043

来源: Elsevier

【 摘 要 】

In Japan, there are currently no reliable rating scales for the evaluation of subjective cognitive impairment in patients with bipolar disorder. We studied the relationship between the Japanese version of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) and objective cognitive assessments in patients with bipolar disorder. We further assessed the reliability and validity of the COBRA. Forty-one patients, aged 16-64, in a remission period of bipolar disorder were recruited from Hokkaido University Hospital in Sapporo, Japan. The COBRA (Japanese version) and Frankfurt Complaint Questionnaire (FCQ), the gold standard in subjective cognitive assessment, were administered. A battery of neuropsychological tests was employed to measure objective cognitive impairment. Correlations among the COBRA, FCQ, and neuropsychological tests were determined using Spearman's correlation coefficient. The Japanese version of the COBRA had high internal consistency, good retest reliability, and concurrent validity as indicated by a strong correlation with the FCQ. A significant correlation was also observed between the COBRA and objective cognitive measurements of processing speed. These findings are the first to demonstrate that the Japanese version of the COBRA may be clinically useful as a subjective cognitive impairment rating scale in Japanese patients with bipolar disorder.

【 授权许可】

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