Prospective associations of physical fitness and cognitive performance among inpatients with Schizophrenia

PSYCHIATRY RESEARCH

卷:270

Article

Chen, Li-Jung^1,2  Hao, Julie Christina³  Ku, Po-Wen⁴  Stubbs, Brendon^5,6 

[1] Natl Taiwan Univ Sport, Dept Exercise Hlth Sci, 271 Lixing Rd, Taichung 404, Taiwan

[2] Natl Taiwan Univ Sport, Grad Inst Recreat Sport Management, 271 Lixing Rd, Taichung 404, Taiwan

[3] Minist Hlth & Welf, Tsaotun Psychiat Ctr, Dept Occupat Therapy, 161 Yu Pin Rd, Caotun Township 542, Nan Tou County, Taiwan

[4] Natl Changhua Univ Educ, Grad Inst Sports & Hlth, 1 Jin De Rd, Changhua 500, Taiwan

[5] South London & Maudsley NHS Fdn Trust, Physiotherapy Dept, Denmark Hill, London SE5 8AZ, England

[6] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychol Med, De Crespigny Pk, London SE5 8AF, England

关键词: Exercise;    Fitness;    Physical activity;    Psychiatric disorder;    Cognition;    Recovery;   

DOI  :  10.1016/j.psychres.2018.10.044

来源: Elsevier

【 摘 要 】

There is a paucity of longitudinal research investigating fitness and cognitive performance in people with schizophrenia. This study examined the prospective associations of physical fitness and cognitive performance among inpatients with schizophrenia. A prospective cohort study over two years was undertaken in 190 inpatients with schizophrenia. Four domains of physical fitness (body composition, muscle endurance, flexibility, and cardiovascular fitness) were measured at baseline in addition to the cognitive domains of attention, hand dexterity and working memory. At baseline, compared to general population normative data, more than one third of the sample had poor cardiovascular fitness, and over half were overweight/obese, had poor muscular fitness and poor flexibility. In the schizophrenia sample, better cardiovascular fitness at baseline was significantly associated with better attention, dexterity, and memory. However, the relationships dissipated after adjusting for baseline cognitive scores. In the final models, aside from baseline cognitive scores, only illness duration was significantly associated with dexterity, and smoking status and duration of hospitilization were associated with working memory. Our data suggest that in a cohort of people with established schizophrenia who already had evidence of cognitive dysfunction, better physical fitness was not associated with improved cognitive performance over two years.

【 授权许可】

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