Prevalence and correlates of DSM-5 major depressive and related disorders in the community

PSYCHIATRY RESEARCH

卷:250

Article

Vandeleur, Caroline L.¹  Fassassi, Sylfa¹  Castelao, Enrique¹  Glaus, Jennifer^1,2  Strippoli, Marie-Pierre F.¹  Lasserre, Aurelie M.¹  Rudaz, Dominique¹  Gebreab, Sirak¹  Pistis, Giorgio¹  Aubry, Jean-Michel³  Angst, Jules⁴  Preisig, Martin¹ 

[1] Univ Lausanne Hosp, Dept Psychiat, Site Cery, CH-1008 Prilly, Switzerland

[2] NIMH, Intramural Res Program, Genet Epidemiol Res Branch, Bethesda, MD 20892 USA

[3] Univ Hosp Geneva, Dept Mental Hlth & Psychiat, Geneva, Switzerland

[4] Univ Zurich, Hosp Psychiat, CH-8006 Zurich, Switzerland

关键词: Major depression;    Persistent depression;    Subthreshold depression;    Prevalence;    Course;    Comorbidity;    Treatment;   

DOI  :  10.1016/j.psychres.2017.01.060

来源: Elsevier

【 摘 要 】

Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders (PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied the DSM-5 criteria throughout the range of depressive disorders. The aims of the present study were to 1) establish the lifetime prevalence of specific depressive disorders according to the new DSM-5 definitions in a community sample, and 2) determine their clinical relevance in terms of socio-demographic characteristics, comorbidity, course and treatment patterns. The semi-structured Diagnostic Interview for Genetic Studies was administered by masters-level psychologists to a random sample of an urban area (n=3720). The lifetime prevalence was 15.2% for PDD with persistent major depressive episode (MDE), 3.3% for PDD with pure dysthymia, 28.2% for Major Depressive Disorder (MDD) and 9.1% for OSDD. Subjects with PDD with persistent MDE were the most severely affected, followed by those with recurrent MDD, single episode MDD, PDD with pure dysthymia and OSDD and finally those without depressive disorders. Our data provide further evidence for the clinical significance of mild depressive disorders (OSDD), but cast doubt on the pertinence of lumping together PDD with persistent MDE and the former DSM-IV dysthymic disorder within the new PDD category.

【 授权许可】

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