期刊论文详细信息
NEUROPSYCHOLOGIA 卷:71
Face processing in autism spectrum disorders: From brain regions to brain networks
Review
Nomi, Jason S.1  Uddin, Lucina Q.1,2 
[1] Univ Miami, Dept Psychol, Coral Gables, FL 33124 USA
[2] Univ Miami, Miller Sch Med, Neurosci Program, Miami, FL 33136 USA
关键词: Autism;    Faces;    fMRI;    Connectivity;    Social cognition;    Eye gaze;   
DOI  :  10.1016/j.neuropsychologia.2015.03.029
来源: Elsevier
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【 摘 要 】

Autism spectrum disorder (ASD) is characterized by reduced attention to social stimuli including the human face. This hypo-responsiveness to stimuli that are engaging to typically developing individuals may result from dysfunctioning motivation, reward, and attention systems in the brain. Here we review an emerging neuroimaging literature that emphasizes a shift from focusing on hypo-activation of isolated brain regions such as the fusiform gyms, amygdala, and superior temporal sulcus in ASD to a more holistic approach to understanding face perception as a process supported by distributed cortical and subcortical brain networks. We summarize evidence for atypical activation patterns within brain networks that may contribute to social deficits characteristic of the disorder. We conclude by pointing to gaps in the literature and future directions that will continue to shed light on aspects of face processing in autism that are still under-examined. In particular, we highlight the need for more developmental studies and studies examining ecologically valid and naturalistic social stimuli. (C) 2015 Elsevier Ltd. All rights reserved.

【 授权许可】

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