Understanding the role of the primary somatosensory cortex: Opportunities for rehabilitation

NEUROPSYCHOLOGIA

卷:79

Article

Borich, M. R.¹  Brodie, S. M.²  Gray, W. A.¹  Ionta, S.^3,4,5  Boyd, L. A.^1,6,7 

[1] Emory Univ, Sch Med, Dept Rehabil Med, Div Phys Therapy, Atlanta, GA 30307 USA

[2] Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC, Canada

[3] Univ Hosp Ctr, Dept Radiol, Lab Invest Neurophysiol LINE, Lausanne, Switzerland

[4] Univ Hosp Ctr, Dept Clin Neurosci, Lausanne, Switzerland

[5] Univ Lausanne, Lausanne, Switzerland

[6] Univ British Columbia, Brain Behav Lab, Vancouver, BC V5Z 1M9, Canada

[7] Univ British Columbia, Djavad Mowafaghian Ctr Brain Hlth, Vancouver, BC V5Z 1M9, Canada

关键词: Primary somatosensory cortex;    Rehabilitation;    Motor control;    Motor learning;    Neuroimaging;    Noninvasive brain stimulation;    Stroke;   

DOI  :  10.1016/j.neuropsychologia.2015.07.007

来源: Elsevier

【 摘 要 】

Emerging evidence indicates impairments in somatosensory function may be a major contributor to motor dysfunction associated with neurologic injury or disorders. However, the neuroanatomical substrates underlying the connection between aberrant sensory input and ineffective motor output are still under investigation. The primary somatosensory cortex (S1) plays a critical role in processing afferent somatosensory input and contributes to the integration of sensory and motor signals necessary for skilled movement. Neuroimaging and neurostimulation approaches provide unique opportunities to non-invasively study S1 structure and function including connectivity with other cortical regions. These research techniques have begun to illuminate casual contributions of abnormal S1 activity and connectivity to motor dysfunction and poorer recovery of motor function in neurologic patient populations. This review synthesizes recent evidence illustrating the role of S1 in motor control, motor learning and functional recovery with an emphasis on how information from these investigations may be exploited to inform stroke rehabilitation to reduce motor dysfunction and improve therapeutic outcomes. (C) 2015 Elsevier Ltd. All rights reserved.

【 授权许可】

Free