Localization and patterns of Cerebral dyschromatopsia: A study of subjects with prospagnosia

NEUROPSYCHOLOGIA

卷:89

Article

Moroz, Daniel^1,2,3,4  Corrow, Sherryse L.^1,2,3  Corrow, Jeffrey C.^1,2,3  Barton, Alistair R. S.⁵  Duchaine, Brad⁶  Barton, Jason J. S.^1,2,3 

[1] Univ British Columbia, Human Vis & Eye Movement Lab, Dept Med Neurol, Vancouver, BC, Canada

[2] Univ British Columbia, Human Vis & Eye Movement Lab, Dept Ophthalmol, Vancouver, BC, Canada

[3] Univ British Columbia, Human Vis & Eye Movement Lab, Dept Visual Sci, Vancouver, BC, Canada

[4] Univ Calgary, Calgary, AB, Canada

[5] McGill Univ, Dept Phys, Montreal, PQ, Canada

[6] Dartmouth Coll, Psychol & Brain Sci, Hanover, NS USA

关键词: Hue discrimination;    Colour perception;    Face recognition;    Fourier analysis;    Fusiform gyrus;   

DOI  :  10.1016/j.neuropsychologia.2016.06.012

来源: Elsevier

【 摘 要 】

Objective: Cerebral dyschromatopsia is sometimes associated with acquired prosopagnosia. Given the variability in structural lesions that cause acquired prosopagnosia, this study aimed to investigate the structural correlates of prosopagnosia-associated dyschromatopsia, and to determine if such colour processing deficits could also accompany developmental prosopagnosia. In addition, we studied whether cerebral dyschromatopsia is typified by a consistent pattern of hue impairments. Methods: We investigated hue discrimination in a cohort of 12 subjects with acquired prosopagnosia and 9 with developmental prosopagnosia, along with 42 matched controls, using the Farnsworth-Munsell 100-hue test. Results: We found impaired hue discrimination in six subjects with acquired prosopagnosia, five with bilateral and one with a unilateral occipitotemporal lesion. Structural MRI analysis showed maximum overlap of lesions in the right and left lingual and fusiform gyri. Fourier analysis of their error scores showed tritanopic-like deficits and blue-green impairments, similar to tendencies displayed by the healthy controls. Three subjects also showed a novel fourth Fourier component, indicating additional peak deficits in purple and green-yellow regions. No subject with developmental prosopagnosia had impaired hue discrimination. Conclusions: In our subjects with prosopagnosia, dyschromatopsia occurred in those with acquired lesions of the fusiform gyri, usually bilateral but sometimes unilateral. The dyschromatopsic deficit shows mainly an accentuation of normal tritatanopic-like tendencies. These are sometimes accompanied by additional deficits, although these could represent artifacts of the testing procedure. (C) 2016 Elsevier Ltd. All rights reserved.

【 授权许可】

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