A preliminary investigation of sleep quality in functional neurological disorders: Poor sleep appears common, and is associated with functional impairment

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:378

Article

Graham, Christopher D.^1,2  Kyle, Simon D.³ 

[1] Univ Leeds, Leeds Inst Hlth Sci, Worsley Bldg, Leeds LS2 9LJ, W Yorkshire, England

[2] St James Univ Hosp, Leeds Teaching Hosp NHS Trust, Dept Clin Neuropsychol, Leeds LS9 7TF, W Yorkshire, England

[3] Univ Oxford, Nuffield Dept Clin Neurosci, Sleep & Circadian Neurosci Inst, Oxford 0X3 9DU, England

关键词: Functional neurological disorders;    Dissociative seizures;    Psychogenic nonepileptic seizures;    Functional motor symptoms;    Functional movement disorder;    Conversion disorder;    Sleep;    Insomnia;   

DOI  :  10.1016/j.jns.2017.05.021

来源: Elsevier

【 摘 要 】

Purpose: Functional neurological disorders (FND) are disabling conditions for which there are few empirically supported treatments. Disturbed sleep appears to be part of the FND context; however, the clinical importance of sleep disturbance (extent, characteristics and impact) remains largely unknown. We described sleep quality in two samples, and investigated the relationship between sleep and FND-related functional impairment. Methods: We included a sample recruited online via patient charities (N = 205) and a consecutive clinical sample (N = 20). Participants completed validated measures of sleep quality and sleep characteristics (e.g. total sleep time, sleep efficiency), mood, and FND-related functional impairment. Results: Poor sleep was common in both samples (89% in the clinical range), which was characterised by low sleep efficiency (M = 65.40%) and low total sleep time (M = 6.05 h). In regression analysis, sleep quality was negatively associated with FND-related functional impairment, accounting for 1.6% of the variance and remaining significant after the introduction of mood variables. Conclusions: These preliminary analyses suggest that subjective sleep disturbance (low efficiency, short sleep) is common in FND. Sleep quality was negatively associated with the functional impairment attributed to FND, independent of depression. Therefore, sleep disturbance may be a clinically important feature of FND. (C) 2017 Elsevier B.V. All rights reserved.

【 授权许可】

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