Neuropathic pain and SCI: Identification and treatment strategies in the 21st century

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:384

Review

Hatch, Maya N.¹  Cushing, Timothy R.²  Carlson, Gregory D.³  Chang, Eric Y.^3,4 

[1] Long Beach Vet Affairs Med Ctr, Spinal Cord Injury Disorder Ctr, Long Beach, CA USA

[2] Univ Calif Los Angeles, Sch Med, Phys Med & Rehabil Dept, Los Angeles, CA USA

[3] Restore Orthoped & Spine Ctr, 1120 W La Veta Ave 300, Orange, CA 92868 USA

[4] Long Beach Vet Affairs Med Ctr, Phys Med & Rehabil Dept, Long Beach, CA USA

关键词: Spinal cord injury;    Neuropathic pain measures;    Neuropathic pain;    Pain classification;    Pain management;    SCI pain treatment;    ISCIP;   

DOI  :  10.1016/j.jns.2017.11.018

来源: Elsevier

【 摘 要 】

Pain is a common complication in patients following spinal cord injury (SCI), with studies citing up to 80% of patients reporting some form of pain. Neuropathic pain (NP) makes up a substantial percentage of all pain symptoms in patients with SCI and is often complex. Given the high prevalence of NP in patients with SCI, proper identification and treatment is imperative. Indeed, identification of pain subtypes is a vital step toward determining appropriate treatment. A variety of pharmacological and non-pharmacological treatments can be undertaken including antiepileptics, tricyclic antidepressants, opioids, transcranial direct current stimulation, and invasive surgical procedures. Despite all the available treatment options and advances in the field of SCI medicine, providing adequate treatment of NP after SCI continues to be challenging. It is therefore extremely important for clinicians to have a strong foundation in the identification of SCI NP, as well as an understanding of appropriate treatment options. Here, we highlight the definitions and classification tools available for NP identification, and discuss current treatment options. We hope that this will not only provide a better understanding of NP for physicians in various subspecialties, but that it will also help guide future research on this subject.

【 授权许可】

Free