A Neurodegenerative Disease Sleep Questionnaire: Principal component analysis in Parkinson's disease

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:336

Article

Scullin, Michael K.¹  Harrison, Tyler L.²  Factor, Stewart A.¹  Bliwise, Donald L.¹ 

[1] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA 30329 USA

[2] Georgia Inst Technol, Sch Psychol, Atlanta, GA 30332 USA

关键词: Sleep questionnaire;    Principal component analysis;    Nocturia;    Sleep disordered breathing;    Dreaming;    Restless legs syndrome;    Neurodegenerative disease;    Parkinson's disease;   

DOI  :  10.1016/j.jns.2013.09.009

来源: Elsevier

【 摘 要 】

Sleep disturbances are common in many neurodegenerative diseases and may include altered sleep duration, fragmented sleep, nocturia, excessive daytime sleepiness, and vivid dreaming experiences, with occasional parasomnias. Although representing the gold standard, polysomnography is not always cost-effective or available for measuring sleep disturbance, particularly for screening. Although numerous sleep-related questionnaires exist, many focus-on a specific sleep disturbance (e.g., restless legs, REM Behavior Disorder) and do not capture efficiently the variety of sleep issues experienced by such patients. We administered the 12-item Neurodegenerative Disease Sleep Questionnaire (NDSQ) and the Epworth Sleepiness Scale to 145 idiopathic Parkinson's disease patients. Principal component analysis using eigenvalues greater than 1 suggested five separate components: sleep quality (e.g., sleep fragmentation), nocturia, vivid dreams/nightmares, restless legs symptoms, and sleep-disordered breathing. These results demonstrate construct validity of our sleep questionnaire and suggest that the NDSQ may be a useful screening tool for sleep disturbances in at least some types of neurodegenerative disorders. (C) 2013 Elsevier B.V. All rights reserved.

【 授权许可】

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