The association between cigarette smoking and multiple sclerosis

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:311

Article

Jafari, Naghmeh¹  Hintzen, Rogier Q.¹ 

[1] Erasmus MC, Dept Neurol, ErasMS, NL-3000 CA Rotterdam, Netherlands

关键词: Multiple sclerosis;    Cigarette smoking;    Environmental risk factors;    Clinical course;   

DOI  :  10.1016/j.jns.2011.09.008

来源: Elsevier

【 摘 要 】

Genetic factors partially explain the susceptibility of multiple sclerosis (MS) and might even relate to the clinical course. Still, many epidemiological studies point at an important role for environmental factors in MS. Smoking is one of the major candidates. In this review we provide an overview of the epidemiological studies on cigarette smoking and the association on MS risk and MS clinical course. In addition, we discuss the possible biological pathways that may influence neurological damage in MS. Moreover, the relation of smoking with other environmental MS risk factors will be addressed. (C) 2011 Elsevier B.V. All rights reserved.

【 授权许可】

Free