ISHLT Consensus Statement on adult and pediatric airway complications after lung transplantation: Definitions, grading system, and therapeutics

JOURNAL OF HEART AND LUNG TRANSPLANTATION

卷:37

Article

Crespo, Maria M.¹  McCarthy, Daniel P.²  Hopkins, Peter M.³  Clark, Stephen C.⁴  Budev, Marie⁵  Bermudez, Christian A.⁶  Benden, Christian⁷  Eghtesady, Pirooz⁸  Lease, Erika D.⁹  Leard, Lorriana¹⁰  D'Cunha, Jonathan¹¹  Wigfield, Christopher H.¹²  Cypel, Marcelo¹³  Diamond, Joshua M.¹  Yun, James J.¹⁴  Yarmus, Lonny¹⁵  Machuzak, Michael⁵  Klepetko, Walter¹⁶  Verleden, Geert¹⁷  Hoetzenecker, Konrad¹⁶  Dellgren, Goran¹⁸  Mulligan, Michael¹⁹ 

[1] Hosp Univ Penn, Div Pulm Allergy & Crit Care Med, 3400 Spruce St,9037 Gates Bldg, Philadelphia, PA 19104 USA

[2] Univ Wisconsin, Sch Med, Div Cardiothorac Surg, Madison, WI USA

[3] Prince Charles Hosp, Brisbane, Qld, Australia

[4] Freeman Rd Hosp, Cardiothorac Div, Newcastle Upon Tyne, Tyne & Wear, England

[5] Cleveland Clin, Resp Inst, Cleveland, OH 44106 USA

[6] Hosp Univ Penn, Div Cardiothorac Surg, 3400 Spruce St, Philadelphia, PA 19104 USA

[7] Univ Hosp Zurich, Dept Pulm Med, Zurich, Switzerland

[8] Washington Univ, Sch Med, Div Pediat Cardiothorac Surg, St Louis, MO USA

[9] Univ Washington, Div Pulm & Crit Care Med, Seattle, WA 98195 USA

[10] Univ Calif San Francisco, Med Ctr, Div Pulm & Crit Care Med, San Francisco, CA USA

[11] Univ Pittsburgh, Med Ctr, Dept Cardiothorac Surg, Pittsburgh, PA USA

[12] Advocate Christ Med Ctr, Div Cardiothorac Surg, Chicago, IL USA

[13] Toronto Gen Hosp UHN, Div Thorac Surg, Toronto, ON, Canada

[14] Yale Univ, Sch Med, Div Cardiothorac Surg, New Haven, CT USA

[15] Johns Hopkins Univ Hosp, Div Pulm & Crit Care, Baltimore, MD USA

[16] Vienna Med Univ, Dept Thorac Surg, Vienna, Austria

[17] Univ Hosp Gasthuisberg, Dept Resp Dis, Leuven, Belgium

[18] Sahlgrens Univ Hosp, Cardiothorac Dept, Gothenburg, Sweden

[19] Univ Washington, Div Cardiothorac Surg, Seattle, WA 98195 USA

关键词: lung transplantation;    airway complications;    airway ischemia injury;    anastomosis dehiscence;    bronchial stenosis;   

DOI  :  10.1016/j.healun.2018.01.1309

来源: Elsevier

【 摘 要 】

Airway complications remain a major cause of morbidity and mortality after cardiothoracic transplantation. The reported incidence of airway ischemic complications varies widely, contributed to by the lack of a universally accepted grading system and standardized definitions. Furthermore, the majority of the existing classification systems fail to integrate the wide range of possible bronchial complications that may develop after lung transplant. Hence, a Working Group was created by the International Society for Heart and Lung Transplantation with the aim of elaborating a universal definition of adult and pediatric airway complications and grading system. One such area of focus is to understand the problem in the context of a more standardized consensus of classifying airway ischemia. This consensus definition will have major clinical, therapeutics, and research implications. (C) 2018 International Society for Heart and Lung Transplantation. All rights reserved.

【 授权许可】

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