Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation

JOURNAL OF HEART AND LUNG TRANSPLANTATION

卷:40

Article

Leard, Lorriana E.¹  Holm, Are M.²  Valapour, Maryam³  Glanville, Allan R.⁴  Attawar, Sandeep⁵  Aversa, Meghan⁶  Campos, Silvia, V⁷  Christon, Lillian M.⁸  Cypel, Marcelo⁶  Dellgren, Goran^9,10  Hartwig, Matthew G.¹¹  Kapnadak, Siddhartha G.¹²  Kolaitis, Nicholas A.¹  Kotloff, Robert M.¹³  Patterson, Caroline M.¹⁴  Shlobin, Oksana A.¹⁵  Smith, Patrick J.¹¹  Sole, Amparo¹⁶  Solomon, Melinda¹⁷  Weill, David¹⁸  Wijsenbeek, Marlies S.¹⁹  Willemse, Brigitte W. M.²⁰  Arcasoy, Selim M.²¹  Ramos, Kathleen J.¹² 

[1] Univ Calif San Francisco, San Francisco, CA 94143 USA

[2] Oslo Univ Hosp, Oslo, Norway

[3] Cleveland Clin, Cleveland, OH 44106 USA

[4] St Vincents Hosp, Sydney, NSW, Australia

[5] Krishna Inst Med Sci Inst Heart & Lung Transplant, Hyderabad, India

[6] Univ Toronto, Toronto, ON, Canada

[7] Univ Sao Paulo, Heart Inst InCor, Med Sch, Sao Paulo, Brazil

[8] Med Univ South Carolina, Mt Pleasant, SC USA

[9] Sahlgrens Univ Hosp, Gothenburg, Sweden

[10] Univ Gothenburg, Gothenburg, Sweden

[11] Duke Univ, Durham, NC USA

[12] Univ Washington, Washington, DC USA

[13] Univ Penn, Philadelphia, PA 19104 USA

[14] Royal Papworth Hosp, Cambridge, England

[15] Inova Fairfax Hosp, Annandale, VA USA

[16] Univ Hosp La Fe, Valencia, Spain

[17] Univ Toronto, Hosp Sick Children, Toronto, ON, Canada

[18] Weill Consulting Grp, New Orleans, LA USA

[19] Univ Med Ctr Rotterdam, Erasmus MC, Rotterdam, Netherlands

[20] Univ Groningen, Univ Med Ctr Groningen, Beatrix Childrens Hosp, Groningen, Netherlands

[21] Columbia Univ, New York, NY USA

关键词: consensus;    lung transplant;    emphysema;    chronic obstructive pulmonary disease;    interstitial lung disease;    pulmonary hypertension;    cystic fibrosis;    ethics;    risk factor;   

DOI  :  10.1016/j.healun.2021.07.005

来源: Elsevier

【 摘 要 】

Tens of thousands of patients with advanced lung diseases may be eligible to be considered as potential candidates for lung transplant around the world each year. The timing of referral, evaluation, determination of candidacy, and listing of candidates continues to pose challenges and even ethical dilemmas. To address these challenges, the International Society for Heart and Lung Transplantation appointed an international group of members to review the literature, to consider recent advances in the management of advanced lung diseases, and to update prior consensus documents on the selection of lung transplant candidates. The purpose of this updated consensus document is to assist providers throughout the world who are caring for patients with pulmonary disease to identify potential candidates for lung transplant, to optimize the timing of the referral of these patients to lung transplant centers, and to provide transplant centers with a framework for evaluating and selecting candidates. In addition to addressing general considerations and providing disease specific recommendations for referral and listing, this updated consensus document includes an ethical framework, a recognition of the variability in acceptance of risk between transplant centers, and establishes a system to account for how a combination of risk factors may be taken into consideration in candidate selection for lung transplantation. (C) 2021 The Author(s). Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.

【 授权许可】

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