Differential regenerative ability of sensory and motor neurons

NEUROSCIENCE LETTERS

卷:652

Review

Cheah, Menghon¹  Fawcett, James W.¹  Haenzi, Barbara¹ 

[1] Univ Cambridge, John van Geest Ctr Brain Repair, Cambridge CB2 0PY, England

关键词: Spinal cord;    Regeneration;    Sensory neurons;    Motor neurons;    Grafts;   

DOI  :  10.1016/j.neulet.2016.11.004

来源: Elsevier

【 摘 要 】

After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve functional sensory and motor regeneration. As these two types of neurons respond differently to axotomy, growth environment and treatment, the future challenge will be on how to achieve full recovery in a way that allows regeneration of both types of fibres simultaneously. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free