STRAIN DIFFERENCE IN PHENYLETHANOLAMINE N-METHYLTRANSFERASE ACTIVITY AND IMMUNOREACTIVITY OF MEDULLA-OBLONGATA OF SPRAGUE-DAWLEY AND LONG-EVANS HOODED RATS

NEUROSCIENCE LETTERS

卷:128

Article

PARK, DH ; PARK, HS ; JOH, TH ; ANWAR, M ; RUGGIERO, DA

关键词: PHENYLETHANOLAMINE N-METHYLTRANSFERASE;    TYROSINE HYDROXYLASE;    MEDULLA-OBLONGATA;    IMMUNOCYTOCHEMISTRY;    SPRAGUE-DAWLEY RAT;    LONG-EVANS RAT;    STRAIN DIFFERENCE;   

DOI  :  10.1016/0304-3940(91)90269-Y

来源: Elsevier

【 摘 要 】

Previously, we reported that retinal phenylethanolamine N-methyltransferase (PNMT) activity of Sprague-Dawley (SD) rats was significantly higher than that of Long-Evans (LE) hooded rats. However, there were no noticeable differences observed in PNMT-immunostaining patterns between the retinae of LE and SD rats. In order to examine this discrepancy, we extended this study to areas of the medulla oblongata harboring PNMT-containing cell bodies. In the present report, we demonstrate that the enzyme activity as well as the immunoreactivity of PNMT in medulla oblongata of SD rats were significantly higher than that observed in the LE strain.

【 授权许可】

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