The role of the frontopolar cortex in manipulation of integrated information in working memory

NEUROSCIENCE LETTERS

卷:595

Article

Kim, Chobok¹  Kroger, James K.^2,3  Calhoun, Vince D.^4,5  Clark, Vincent P.^3,5 

[1] Kyungpook Natl Univ, Dept Psychol, Daegu 702701, South Korea

[2] New Mexico State Univ, Dept Psychol, Las Cruces, NM 88003 USA

[3] Univ New Mexico, Dept Psychol, Albuquerque, NM 87131 USA

[4] Univ New Mexico, Dept Elect & Comp Engn, Albuquerque, NM 87131 USA

[5] Mind Res Network, Albuquerque, NM USA

关键词: Functional MRI;    Frontopolar cortex;    Dorsolateral prefrontal cortex;    Working memory;    Manipulation;    Integration;   

DOI  :  10.1016/j.neulet.2015.03.044

来源: Elsevier

【 摘 要 】

Cognitive operations often require integration of information. Previous studies have shown that, integration of information in working memory recruits frontopolar cortex (FPC). In this fMRI study, we sought to reveal neural mechanisms of FPC underlying the integration of information during arithmetic tasks. We compared a condition requiring manipulation of two features of an item held in working memory with manipulation of one feature. The results showed that, FPC was equally recruited in both conditions, while dorsolateral prefrontal cortex (DLPFC) tended to be moreactivated when manipulating two features. We suggest that, FPC plays an integrative role and is recruited by the production of representations in accordance with task constraints, whereas DLPFC appears to be sensitive to processing demands induced by the manipulation of information. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free