CIRRHOSIS OF THE HUMAN LIVER - AN IN-VITRO P-31 NUCLEAR-MAGNETIC-RESONANCE STUDY

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

卷:1272

Article

TAYLORROBINSON, SD ; THOMAS, EL ; SARGENTONI, J ; MARCUS, CD ; DAVIDSON, BR ; BELL, JD

关键词: NMR, P-31;    CIRRHOSIS;    PHOSPHOLIPID;    HUMAN;    LIVER;   

DOI  :  10.1016/0925-4439(95)00074-E

来源: Elsevier

【 摘 要 】

Human livers with histologically proven cirrhosis were assessed using in vitro P-31 NMR spectroscopy. Spectra were compared with those from histologically normal livers and showed significant elevations in phosphoethanolamine (PE) and phosphocholine (PC) and significant reductions in glycerophosphorylethanolamine (GPE) and glycerophosphorylcholine (GPC), There were no significant differences in spectra from livers with compensated and decompensated cirrhosis. These results help to characterise the alterations in membrane metabolism in cirrhosis of the liver.

【 授权许可】

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