An efficient palladium-catalyzed synthesis of benzils from aryl bromides: vinylene carbonate as a synthetic equivalent of glyoxal

TETRAHEDRON LETTERS

卷:52

Article

Kim, Jae Nyoung¹ 

[1] Chonnam Natl Univ, Dept Chem, Kwangju 500757, South Korea

关键词: Benzils;    Vinylene carbonate;    Palladium;    Glyoxal;    Aerobic oxidation;   

DOI  :  10.1016/j.tetlet.2011.04.108

来源: Elsevier

【 摘 要 】

An expedient synthetic procedure of benzil derivatives from aryl bromides was developed using vinylene carbonate as a glyoxal equivalent in a palladium-catalyzed reaction. The reaction involved a sequential diarylation of vinylene carbonate to form 4,5-diaryl-1,3-dioxo1-2-one, ring-opening to benzoin derivative, and an oxidation process. (C) 2011 Elsevier Ltd. All rights reserved.

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