Copper-catalyzed amination of potassium aryl trifluoroborates using aqueous ammonia

TETRAHEDRON LETTERS

卷:53

Article

Liesen, Andre P.¹  Silva, Arisson T.¹  Sousa, Jokderlea C.¹  Menezes, Paulo H.¹  Oliveira, Roberta A.¹ 

[1] Univ Fed Pernambuco, Dept Quim Fundamental, BR-50740540 Recife, PE, Brazil

关键词: Potassium organotrifluoroborates;    Aromatic amines;    Aqueous ammonia;   

DOI  :  10.1016/j.tetlet.2012.06.011

来源: Elsevier

【 摘 要 】

The conversion of potassium aryl trifluoroborates containing different functionalities into the corresponding aryl amines using a catalytic amount of CuSO4 center dot 5H(2)O is described. The methodology uses water as a solvent under aerobic conditions to give the products in good yields. (C) 2012 Elsevier Ltd. All rights reserved.

【 授权许可】

Free