Efficient C3-alkylsulfenylation of indoles under mild conditions using Lewis acid-activated 8-quinolinethiosulfonates

TETRAHEDRON LETTERS

卷:65

Article

Galardon, Erwan¹ 

[1] Univ Paris, LCBPT, UMR 8601, CNRS, 45 Rue Sts Peres, F-75006 Paris, France

关键词: Sulfenylation;    Thiosulfonate;    Indole;    Lewis acid;    C-S bond;   

DOI  :  10.1016/j.tetlet.2020.152748

来源: Elsevier

【 摘 要 】

The activation of 8-quinolinethiosulfonates by zinc chloride promotes the usually difficult to achieve C3-alkylsulfenylation of indoles at room temperature under aerobic conditions. This strategy is compatible with substrates containing various functional groups. (C) 2021 Elsevier Ltd. All rights reserved.

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