Propargylation of aromatic compounds using Ce(OTf)3 as catalyst

TETRAHEDRON LETTERS

卷:53

Article

Silveira, Claudio C.¹  Mendes, Samuel R.²  Martins, Guilherme M.¹ 

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Univ Estado Santa Catarina, GAPAM, Dept Quim, BR-89219719 Joinville, SC, Brazil

关键词: Propargylation;    Propargylic alcohol;    Aromatic substitution;    Cerium(III) triflate;   

DOI  :  10.1016/j.tetlet.2012.01.046

来源: Elsevier

【 摘 要 】

Ce(OTf)(3) was successfully employed as catalyst for the activation of the hydroxyl group in the Friedel-Crafts reaction of aromatic compounds with propargylic alcohols in nitromethane. The products were obtained in good to excellent yields. (C) 2012 Elsevier Ltd. All rights reserved.

【 授权许可】

Free