Copper nanoparticles in click chemistry: an alternative catalytic system for the cycloaddition of terminal alkynes and azides

TETRAHEDRON LETTERS

卷:50

Article

Alonso, Francisco^1,2  Moglie, Yanina^1,2,3  Radivoy, Gabriel³  Yus, Miguel^1,2 

[1] Univ Alicante, Fac Ciencias, Dept Quim Organ, E-03080 Alicante, Spain

[2] Univ Alicante, ISO, E-03080 Alicante, Spain

[3] Univ Nacl Sur, Inst Quim Sur INQUISUR, Dept Quim, RA-8000 Bahia Blanca, Buenos Aires, Argentina

关键词: Click chemistry;    Cycloaddition;    Alkynes;    Azides;    Copper nanoparticles;   

DOI  :  10.1016/j.tetlet.2009.02.220

来源: Elsevier

【 摘 要 】

Readily prepared copper nanoparticles have been found to effectively catalyse the 1,3-dipolar cycloaddition of a variety of azides and alkynes furnishing the corresponding 1,2,3-triazoles in excellent yields. Both the preparation of the nanoparticles and the click reaction proceed in short reaction times. (C) 2009 Elsevier Ltd. All rights reserved.

【 授权许可】

Free