Raney-Ni catalyzed conversion of levulinic acid to 5-methyl-2-pyrrolidone using ammonium formate as the H and N source

TETRAHEDRON LETTERS

卷:59

Article

Amarasekara, Ananda S.¹  Lawrence, Yen Maroney¹ 

[1] Prairie View A&M Univ, Dept Chem, Prairie View, TX 77446 USA

关键词: Levulinic acid;    5-Methyl-2-pyrrolidone;    gamma-Valerolactone;    Ammonium formate;    Raney-Ni;   

DOI  :  10.1016/j.tetlet.2018.03.087

来源: Elsevier

【 摘 要 】

Renewable biomass based levulinic acid was converted to 5-methyl-2-pyrrolidone in 94% yield by a Raney-Ni catalyzed process using ammonium formate in aqueous medium and heating at 180 degrees C for 3 h. The Raney-Ni could be reused for four catalytic cycles with about 10% loss in catalytic activity. In a similar reaction levulinic acid could be converted 1-substituted-5-methyl-2-pyrrolidones in 90-95% yield by using a mixture of formic acid and the corresponding primary amine. (C) 2018 Elsevier Ltd. All rights reserved.

【 授权许可】

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