Bismuth(III) bromide in organic synthesis. A catalytic method for the allylation of tetrahydrofuranyl and tetrahydropyranyl ethers

TETRAHEDRON LETTERS

卷:51

Article

Krabbe, Scott W.¹  Angeles, Veronica V.¹  Mohan, Ram S.¹ 

[1] Illinois Wesleyan Univ, Lab Environm Friendly Organ Synth, Dept Chem, Bloomington, IL 61701 USA

关键词: Allylation;    THP ethers;    Bismuth bromide;    Acetates;   

DOI  :  10.1016/j.tetlet.2010.08.079

来源: Elsevier

【 摘 要 】

A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products. (C) 2010 Elsevier Ltd. All rights reserved.

【 授权许可】

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