Ionic liquid promoted synthesis of heterocycle-fused pyrimidine-2,4 (1H,3H)-diones utilising CO2

TETRAHEDRON LETTERS

卷:59

Article

Li, Chun¹  Lu, Xunhua¹  Yang, Yuanyong¹  Yang, Shenggang¹  Zhang, Lin¹ 

[1] Guizhou Med Univ, Dept Pharm, Guiyang 550004, Guizhou, Peoples R China

关键词: Ionic liquid;    Carbon dioxide;    Green chemistry;    Heterocycles;    Pyrimidine-2,4(1H,3H)-diones;   

DOI  :  10.1016/j.tetlet.2018.05.043

来源: Elsevier

【 摘 要 】

An efficient ionic liquid system was developed for the preparation of various heterocycle-fused pyrimidine-2, 4(1H,3H)-diones in moderate to excellent yields (52-95%). It was found that [HDBN+][TFE-], a simple and easily prepared ionic liquid, could act as both the solvent and reaction promoter, and that the reactions could be efficiently carried out at atmospheric pressures of CO2. (C) 2018 Elsevier Ltd. All rights reserved.

【 授权许可】

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