Green synthesis of novel chalcone and coumarin derivatives via Suzuki coupling reaction

TETRAHEDRON LETTERS

卷:53

Article

Vieira, Lucas C. C.¹  Paixao, Marcio Weber¹  Correa, Arlene G.¹ 

[1] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil

关键词: Suzuki reaction;    Chalcone;    Coumarin;    Microwaves;    Green technology;   

DOI  :  10.1016/j.tetlet.2012.03.079

来源: Elsevier

【 摘 要 】

Chalcones and coumarins are important naturally occurring plant constituents and display a wide range of pharmacological and biological activities. In an environmentally benign approach, synthesis of biphenyl chalcone and coumarin derivatives was successfully accomplished via Suzuki coupling by using PEG-400 as a solvent under microwave irradiation. Salient feature of this methodology includes: short reaction time, good to excellent yields, and prominent tolerance of different functional groups. (C) 2012 Elsevier Ltd. All rights reserved.

【 授权许可】

Free