One-pot multicomponent synthesis of 2,3-dihydropyrans: new access to furanose-pyranose 1,3-C-C-linked-disaccharides

TETRAHEDRON LETTERS

卷:50

Article

Castagnolo, Daniele¹  Botta, Lorenzo¹  Botta, Maurizio¹ 

[1] Univ Siena, Dipartimento Farmaco Chim Tecnol, I-53100 Siena, Italy

关键词: Enyne metathesis;    Hetero-Diels-Alder;    Multicomponent reaction;    Dihydropyrans;    Disaccharide;   

DOI  :  10.1016/j.tetlet.2009.01.047

来源: Elsevier

【 摘 要 】

An efficent synthesis of 2,3-dihydropyrans from different terminal alkynes was developed. The 2,3-dihydropyrans were obtained in a few minutes through a microwave-assisted multicomponent enyne cross-metathesis/hetero-Diels-Alder reaction. Starting from C-ethynyl-ribofuranose, a new multicomponent approach to furanose-pyramose 1,3-C-C-linked disaccharides was also developed. (C) 2009 Elsevier Ltd. All rights reserved.

【 授权许可】

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