New chiral 1,2-aminoalcohols derived from biomass and their application in diethyl zinc additions

TETRAHEDRON LETTERS

卷:55

Article

Zanardi, Maria M.¹  Botta, Maria C.¹  Suarez, Alejandra G.¹ 

[1] Univ Nacl Rosario, CONICET, Fac Ciencias Bioquim & Farmaceut, Inst Quim Rosario, RA-2000 Rosario, Argentina

关键词: Levoglucosenone;    1,2-Aminoalcohols;    Chiral ligands;    Asymmetric induction;   

DOI  :  10.1016/j.tetlet.2014.08.124

来源: Elsevier

【 摘 要 】

A convenient procedure for the preparation of chiral 1,2-aminoalcohols starting from levoglucosenone, a biomass derivative, is described. The 1,2-aminoalcohols, bearing primary, secondary, and tertiary amino groups, were tested as chiral catalysts in the asymmetric addition of diethyl zinc to benzaldehyde. (C) 2014 Elsevier Ltd. All rights reserved.

【 授权许可】

Free