The cooperative effect of electrostatic and hydrophobic forces in the complexation of cationic molecules by a water-soluble resorcin[4]arene derivative

TETRAHEDRON LETTERS

卷:41

Article

Park, SJ ; Hong, JI

关键词: host-guest complex;    cooperative effect;    water-soluble resorcin[4]arene;   

DOI  :  10.1016/S0040-4039(00)01441-6

来源: Elsevier

【 摘 要 】

A new water-soluble resorcin[4]arene derivative 4 was synthesized and the complexation of cationic guests in D2O was studied by H-1 NMR spectroscopy. A 1:1 binding mode was elucidated by a Job's plot. The cooperative effect of electrostatic and hydrophobic interactions acts as a binding force for a strong complex formation with appropriate cationic guests in water. The thermodynamic parameters of complexation of guest I determined by a van't Hoff plot indicate that the complexation process is both enthalpically and entropically driven. (C) 2000 Elsevier Science Ltd. All rights reserved.

【 授权许可】

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