Accessing nitrosocarbonyl compounds with temporal and spatial control via the photoredox oxidation of N-substituted hydroxylamines

TETRAHEDRON LETTERS

卷:56

Article

Frazier, Charles P.¹  Palmer, Leoni I.¹  Samoshin, Andrey V.¹  de Alaniz, Javier Read¹ 

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

关键词: Hydroxylamine;    Nitrosocarbonyl;    Photoredox;    Temporal and spatial control;    Block co-polymer;   

DOI  :  10.1016/j.tetlet.2015.01.024

来源: Elsevier

【 摘 要 】

Photoredox catalysis is employed to generate highly reactive acylnitroso species from hydroxamic acid derivatives. The conditions are shown to be comparable to a previously developed transition metal aerobic oxidation and are amenable to a range of transformations including Diels-Alder and ene reactions. This unique application of such an approach gives access to temporal and spatial control in nitroso chemistry. Published by Elsevier Ltd.

【 授权许可】

Free