Rapid microwave assisted hydration of internal arylalkynes in the presence of PTSA: an efficient regioselective access to carbonyl compounds

TETRAHEDRON LETTERS

卷:47

Article

Le Bras, Gaelle ; Provot, Olivier ; Peyrat, Jean-Francois ; Alami, Mouad ; Brion, Jean-Daniel

关键词: alkynes;    microwave assisted hydration;    PTSA;    carbonyl compounds;   

DOI  :  10.1016/j.tetlet.2006.05.155

来源: Elsevier

【 摘 要 】

A metal-free procedure for the regioselective hydration of internal arylalkynes under microwave irradiation is described. The reaction promoted by PTSA takes place rapidly in EtOH and regioselectively afforded in good yields various carbonyl compounds 2. (c) 2006 Elsevier Ltd. All rights reserved.

【 授权许可】

Free