An efficient fluoride-mediated O-arylation of sterically hindered halophenols with silylaryl triflates under mild reaction conditions

TETRAHEDRON LETTERS

卷:52

Article

Gebara, Karimi S.¹  Casagrande, Gleison A.¹  Raminelli, Cristiano¹ 

[1] Fundacao Univ Fed Grande Dourados, Fac Ciencias Exatas & Tecnol, BR-79804970 Dourados, MS, Brazil

关键词: O-Arylation;    Functionalized diaryl ethers;    Benzyne chemistry;    Silylaryl triflates;    Mild reaction conditions;   

DOI  :  10.1016/j.tetlet.2011.03.124

来源: Elsevier

【 摘 要 】

The reaction between 2,6-dihalophenols and 2-(trimethylsilyl)aryl triflates in the presence of CsF using acetonitrile as solvent at room temperature led to the formation of functionalized diaryl ethers in very good yields. (C) 2011 Elsevier Ltd. All rights reserved.

【 授权许可】

Free