期刊论文详细信息
JOURNAL OF CARDIAC FAILURE 卷:16
Patient Expectations From Implantable Defibrillators to Prevent Death in Heart Failure
Article
Stewart, Garrick C.1  Weintraub, Joanne R.1  Pratibhu, Parakash P.1  Semigran, Marc J.2  Camuso, Janice M.2  Brooks, Kimberly1  Tsang, Sui W.3  Anello, Mary Susan1  Nguyen, Viviane T.1  Lewis, Eldrin F.1  Nohria, Anju1  Desai, Akshay S.1  Givertz, Michael M.1  Stevenson, Lynne W.1 
[1] Brigham & Womens Hosp, Div Cardiovasc Med, Boston, MA 02115 USA
[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Boston, MA USA
[3] Yale Univ, Sch Epidemiol & Publ Hlth, Dept Biostat, New Haven, CT USA
关键词: Implantable defibrillators;    heart failure;    sudden death;    cardiomyopathy;   
DOI  :  10.1016/j.cardfail.2009.09.003
来源: Elsevier
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【 摘 要 】

Background: Indications for implantable cardioverter-defibrillators (ICDs) in heart failure (HF) are expanding and may include more than 1 million patients. This study examined patient expectations from ICDs for primary prevention of sudden death in HF. Methods and Results: Study participants (n = 105) had an EF <35% and symptomatic HF, without history of ventricular tachycardia/fibrillation or syncope. Subjects completed a written survey about perceived ICD benefits, survival expectations, and circumstances under which they might deactivate defibrillation. Mean age was 58, LVEF 21%, 40% were New York Heart Association Class and 65% already had a primary prevention ICD. Most patients anticipated more than 10 years survival despite symptomatic HF. Nearly 54% expected an ICD to save >= 50 lives per 100 during 5 years. ICD recipients expressed more confidence that the device would save their own lives compared with those without an ICD (P < .001). Despite understanding the ease of deactivation, 70% of ICD recipients indicated they would keep the ICD on even if dying of cancer, 55% even if having daily shocks, and none would inactivate defibrillation even if suffering constant dyspnea at rest. Conclusions: HE patients anticipate long survival, overestimate survival benefits conferred by ICDs, and express reluctance to deactivate their devices even for end-stage disease. (J Cardiac Fail 2010:16:106-113)

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