Application of intraarterial superselective indocyanine green angiography in bypass surgery for adult moyamoya disease

Frontiers in Neurology

Neurology

Chenhui Zhou¹  Yiwen Wu¹  Xianru Li¹  Yi Huang¹  Haojin Ni¹  Shengjun Zhou¹  Zhimeng Zhang¹  Haifeng Wang¹  Jinghui Lin¹  Wenting Lan² 

[1] Department of Neurosurgery, The First Affiliated Hospital of Ningbo University, Ningbo, China;Department of Radiology, The First Affiliated Hospital of Ningbo University, Ningbo, China;

关键词: moyamoya disease;    cerebral revascularization;    intravenous ICG video-angiography;    intra-arterial ICG video-angiography;    blood flow direction;    cortical perfusion range;   

DOI  :  10.3389/fneur.2023.1241760

 received in 2023-06-17, accepted in 2023-09-25,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundExtracranial-intracranial (EC-IC) bypass surgery is the main treatment approach to moyamoya disease, and an accurate assessment of the patency of anastomosis is critical for successful surgery. So far, the most common way to do this is the intraoperative intravenous indocyanine green (ICG) video-angiography. Intra-arterial ICG-VA has been applied to treat peripheral cerebral aneurysms, spinal arteriovenous fistulas, and dural arteriovenous fistulas, but few reports have concerned the use of arterial injection of ICG to evaluate anastomotic patency. This research aims to explore the feasibility and effects of catheter-guided superficial temporal artery injection of ICG in the evaluation of anastomotic patency after bypass surgery.MethodsIn this study, 20 patients with moyamoya disease or syndrome who underwent bypass surgery were divided into two groups, one who received intravenous ICG angiography and the other who received intra-arterial ICG angiography, to compare the two injection methods for vascular anastomosis patency. We conducted conventional intraoperative digital subtraction angiography (DSA) in a hybrid operating room during extracranial-intracranial (EC-IC) bypass surgery, including the additional step of injecting ICG into the main trunk of the superficial temporal artery (STA) through a catheter.ResultsIntra-arterial injection of indocyanine green video-angiography (ICG-VA) indicated good patency of the vascular anastomosis when compared with conventional digital subtraction angiography (DSA) and intravenous ICG-VA, confirming the feasibility of using the arterial injection of ICG for assessing anastomotic patency. And intra-arterial ICG-VA results in faster visualization than intravenous ICG-VA (p < 0.05). Besides, ICG-VA through arterial injection provided valuable information on the vascular blood flow direction after the bypass surgery, and allowed for visual inspection of the range of cortical brain supply from the superficial temporal artery and venous return from the cortex. Moreover, arterial injection of ICG offered a rapid dye washout effect, reducing the repeat imaging time.ConclusionThis study indicates that intra-arterial ICG-VA has good effects in observing the direction of blood flow in blood vessels and the range of cortical brain supply from the STA, which reflects blood flow near the anastomosis and provides additional information that may allow the postoperative prediction of cerebral hyperperfusion syndrome. However, the procedure of intra-arterial ICG-VA is relatively complicated compared to intravenous ICG-VA.

【 授权许可】

Unknown   
Copyright © 2023 Ni, Wu, Zhou, Li, Zhou, Lan, Zhang, Huang, Wang and Lin.