Changes in insight throughout the natural four-year course of obsessive-compulsive disorder and its association with OCD severity and quality of life

Frontiers in Psychiatry

Psychiatry

Adriaan W. Hoogendoorn¹  Patricia van Oppen²  Anton J. L. M. van Balkom²  Nadja Wolf³  Henny A. D. Visser³  Johanna A. M. du Mortier³ 

[1] Department of Psychiatry, Amsterdam Public Health, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, Netherlands;Department of Psychiatry, Amsterdam Public Health, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, Netherlands;Geestelijke gezondheidszorg (GGZ) inGeest, Specialized Mental Health Care, Amsterdam, Netherlands;Mental Health Care Institute Geestelijke gezondheidszorg (GGZ) Centraal, Amersfoort, Netherlands;

关键词: insight;    OCD;    obsessive-compulsive disorder;    natural course;    severity;    quality of life;   

DOI  :  10.3389/fpsyt.2023.1231293

 received in 2023-05-30, accepted in 2023-09-25,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectivePatients with obsessive-compulsive disorder (OCD) and poor insight show higher symptom severity, lower quality of life (QoL), and a reduced treatment response compared to patients with good insight. Little is known about changes in insight. This study explored the course of insight and its association with OCD severity and QoL among 253 patients with OCD participating in the prospective naturalistic Netherlands Obsessive Compulsive Disorder Association (NOCDA) Study.ResultsIn 70% of the participants with available insight data, the level of insight changed during the four-year course. Insight was most variable in participants with poor insight. Improvement of insight scores was statistically significantly associated with improvement of Y-BOCS scores (r = 0.19), but not with changes in QoL scores. Change in insight in the first 2 years was not statistically significantly predictive of OCD severity or QoL at four-year follow-up.ConclusionThese findings suggest that patients’ levels of insight may change during the natural four-year course of OCD and that improvement in the level of insight have a positive association with improvement in OCD severity.

【 授权许可】

Unknown   
Copyright © 2023 Wolf, du Mortier, van Oppen, Hoogendoorn, van Balkom and Visser.