Acute Brucella infection associated with splenic infarction: a case report and review of the literature

Frontiers in Cellular and Infection Microbiology

Cellular and Infection Microbiology

Xiaohua Li¹  Yuxiang Li¹  Limei Shi¹  Xin Li¹  Shuang Wang¹  Yang Wang¹ 

[1] Center of Infectious Disease and Pathogen Biology, Department of Infectious Diseases, The First Hospital of Jilin University, Changchun, China;

关键词: brucellosis;    Brucella abortus;    splenic infarction;    vasculitis;    acute pancreatitis;   

DOI  :  10.3389/fcimb.2023.1234447

 received in 2023-06-04, accepted in 2023-09-12,  发布年份 2023

来源: Frontiers

【 摘 要 】

Brucella infection often involves multiple organ systems with non-specific clinical manifestations, and cutaneous involvement is uncommon. Splenic infarction and leukocytoclastic vasculitis also rarely occur together in the course of brucellosis infection. We report the case of a 47-year-old man with Brucella combined with splenic infarction. The patient presented with fever; large liver, spleen, and lymph nodes; muscle and joint pain; positive laboratory tests for blood cultures (Brucella abortus); and imaging suggestive of splenic infarction. After treatment with streptomycin, doxycycline, and rifampicin, the patient’s clinical symptoms and splenic damage improved. Detailed history taking, correct interpretation of laboratory results, and knowledge of rare complications of human brucellosis facilitate early diagnosis and treatment of the disease.

【 授权许可】

Unknown   
Copyright © 2023 Shi, Wang, Li, Li, Li and Wang