Towards Chinese text and DNA shift encoding scheme based on biomass plasmid storage

Frontiers in Bioinformatics

Bioinformatics

Xu Yang¹  Langwen Lai¹  Xiaolong Shi¹  Xiaoli Qiang¹  Ming Deng¹  Zheng Kou¹  Yuhao Xie² 

[1] Institute of Computing Science and Technology, Guangzhou University, Guangzhou, China;School of Mathematical Science, Inner Mongolia University, Hohhot, China;

关键词: DNA storage;    Chinese text storage;    DNA shift coding;    plasmid storage;    DNA long double-stranded structure storage;   

DOI  :  10.3389/fbinf.2023.1276934

 received in 2023-08-13, accepted in 2023-09-28,  发布年份 2023

来源: Frontiers

【 摘 要 】

DNA, as the storage medium in organisms, can address the shortcomings of existing electromagnetic storage media, such as low information density, high maintenance power consumption, and short storage time. Current research on DNA storage mainly focuses on designing corresponding encoders to convert binary data into DNA base data that meets biological constraints. We have created a new Chinese character code table that enables exceptionally high information storage density for storing Chinese characters (compared to traditional UTF-8 encoding). To meet biological constraints, we have devised a DNA shift coding scheme with low algorithmic complexity, which can encode any strand of DNA even has excessively long homopolymer. The designed DNA sequence will be stored in a double-stranded plasmid of 744bp, ensuring high reliability during storage. Additionally, the plasmid‘s resistance to environmental interference ensuring long-term stable information storage. Moreover, it can be replicated at a lower cost.

【 授权许可】

Unknown   
Copyright © 2023 Yang, Lai, Qiang, Deng, Xie, Shi and Kou.