The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China

Frontiers in Endocrinology

Endocrinology

Yingying Hu¹  Zhengqi Lian²  Haonan Cheng²  Menglong Wang³  Wei Pan³  Jun Wan⁴  Juan-Juan Qin⁵ 

[1] Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China;Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China;Cardiovascular Research Institute, Wuhan University, Wuhan, China;Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China;Cardiovascular Research Institute, Wuhan University, Wuhan, China;Hubei Key Laboratory of Cardiology, Wuhan, China;Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China;Cardiovascular Research Institute, Wuhan University, Wuhan, China;Hubei Key Laboratory of Cardiology, Wuhan, China;Dong Fureng Institute of Economic and Social Development, Wuhan University, Wuhan, China;Department of Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan, China;Center for Healthy Aging, Wuhan University School of Nursing, Wuhan, China;

关键词: obesity;    body mass index;    waist circumference;    visceral adiposity index;    air pollution;    epidemiologic study;   

DOI  :  10.3389/fendo.2023.1221325

 received in 2023-05-12, accepted in 2023-08-22,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundPrevious animal studies have suggested that air pollution (AP) exposure may be a potential risk factor for obesity; however, there is limited epidemiological evidence available to describe the association of obesity with AP exposure.MethodsA retrospective cross-sectional study was conducted on 11,766 participants across mainland China in 2015. Obesity was assessed using body mass index (BMI), waist circumference (WC), and visceral adiposity index (VAI). The space-time extremely randomized tree (STET) model was used to estimate the concentration of air pollutants, including SO2, NO2, O3, PM1, PM2.5, and PM10, matched to participants’ residential addresses. Logistic regression models were employed to estimate the associations of obesity with outdoor AP exposure. Further stratified analysis was conducted to evaluate whether sociodemographics or lifestyles modified the effects.ResultsIncreased AP exposure was statistically associated with increased odds of obesity. The odds ratio (ORs) and 95% confidence interval (CI) of BMI-defined obesity were 1.21 (1.17, 1.26) for SO2, 1.33 (1.26, 1.40) for NO2, 1.15 (1.10, 1.21) for O3, 1.38 (1.29, 1.48) for PM1, 1.19 (1.15, 1.22) for PM2.5, and 1.11 (1.09, 1.13) for PM10 per 10 μg/m3 increase in concentration. Similar results were found for central obesity. Stratified analyses suggested that elderly participants experienced more adverse effects from all 6 air pollutants than middle-aged participants. Furthermore, notable multiplicative interactions were found between O3 exposure and females as well as second-hand smokers in BMI-defined obesity.ConclusionsThis study suggested that outdoor AP exposure had a significant association with the risk of obesity in the middle-aged and elderly Chinese population. Elderly individuals and women may be more vulnerable to AP exposure.

【 授权许可】

Unknown   
Copyright © 2023 Pan, Wang, Hu, Lian, Cheng, Qin and Wan