Placental weights of neonates born with symptomatic congenital syphilis

Frontiers in Pediatrics

Pediatrics

Shakti Pillay¹  Lloyd Tooke¹  Alan R. Horn¹ 

[1] Neonatal Unit, Groote Schuur Hospital, Cape Town, South Africa;Division of Neonatology, Department of Paediatrics, University of Cape Town, Cape Town, South Africa;

关键词: placenta;    syphilis;    congenital;    heavy;    infection;   

DOI  :  10.3389/fped.2023.1215387

 received in 2023-05-01, accepted in 2023-09-25,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundSyphilis during pregnancy remains an important global health concern causing miscarriage, stillbirth, preterm birth and neonatal death. As part of the fetal infection, placental changes occur which may include a heavier placenta than expected.MethodsA cohort of 50 neonates with symptomatic congenital syphilis has previously been described. This cohort was admitted to Groote Schuur neonatal unit in Cape Town South Africa from 2011 to 2013. For this study, the placental weights of the neonates were analyzed and compared to population based placental centiles.ResultsThere was data for 37 placentae. Heavy placentae (>90th centile) occurred in 76% of placentae in the study. All 6 infants with birth weights ≥2,500 g had heavy placentae. There was no correlation between placental centile and death.ConclusionHeavy placenta are an important and frequent finding with symptomatic congenital syphilis, especially in the larger neonates.

【 授权许可】

Unknown   
© 2023 Pillay, Horn and Tooke.