The role of early detection and treatment in malaria elimination

Malaria Journal

Review

Sasithon Pukrittayakamee¹  Jordi Landier²  Craig A. Bonnington²  Daniel M. Parker²  Verena I. Carrara²  Aung Myint Thu²  Khin Maung Lwin²  Gilles Delmas²  François H. Nosten³ 

[1] Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand;Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand;Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK;

关键词: Malaria;    Falciparum Malaria;    Malaria Incidence;    G6PD Deficiency;    Malaria Elimination;   

DOI  :  10.1186/s12936-016-1399-y

 received in 2016-03-17, accepted in 2016-06-17,  发布年份 2016

来源: Springer

【 摘 要 】

Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP). The main focus of a MP is to provide uninterrupted and rapid access to rapid diagnostic tests (RDTs) and artemisinin-based combination therapy (ACT) too all inhabitants of a village. RDTs allow trained community members to perform malaria diagnosis accurately and prescribe appropriate treatment, reducing as much as possible any delay between the onset of fever and treatment. Early treatment with ACT and with a low-dose of primaquine prevents further transmission from human to mosquito. A functioning MP represents an essential component of any malaria elimination strategy. Implementing large-scale, high-coverage, community-based early diagnosis and treatment through MPs requires few technological innovations but relies on a very well structured organization able to train, supervise and supply MPs, to monitor activity and to perform strict malaria surveillance.

【 授权许可】

CC BY   
© The Author(s) 2016