Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation

BMC Neuroscience

Research Article

Azra Premji¹  Angela Ziluk¹  Aimee J Nelson¹ 

[1] Department of Kinesiology, University of Waterloo, Waterloo, Canada;

关键词: Maximum Voluntary Contraction;    First Dorsal Interosseous;    Repetitive Transcranial Magnetic Stimulation;    Active Motor Threshold;    Paired Associative Stimulation;   

DOI  :  10.1186/1471-2202-11-91

 received in 2010-02-28, accepted in 2010-08-05,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundIntermittent theta-burst stimulation (iTBS) is a form of repetitive transcranial magnetic stimulation that may alter cortical excitability in the primary somatosensory cortex (SI). The present study investigated the effects of iTBS on subcortical and early cortical somatosensory evoked potentials (SEPs) recorded over left, iTBS stimulated SI and the right-hemisphere non-stimulated SI. SEPs were recorded before and at 5, 15, and 25 minutes following iTBS.ResultsCompared to pre-iTBS, the amplitude of cortical potential N20/P25 was significantly increased for 5 minutes from non-stimulated SI and for 15 to 25 minutes from stimulated SI. Subcortical potentials recorded bilaterally remained unaltered following iTBS.ConclusionWe conclude that iTBS increases the cortical excitability of SI bilaterally and does not alter thalamocortical afferent input to SI. ITBS may provide one avenue to induce cortical plasticity in the somatosensory cortex.

【 授权许可】

Unknown   
© Premji et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.