Evolution in the surgical management of gastric cancer: is extended lymph node dissection back in vogue in the USA?

World Journal of Surgical Oncology

Review

Jiayi Yang¹  Xiang Da (Eric) Dong²  Tianxiang Chen³  Dongsheng Yan⁴  Zhiqiang Zheng⁵ 

[1] Department of Clinical Medicine, Jiaxing University, Jiaxing, Zhejiang, China;Department of Surgery, Westchester Medical Center, 100 Woods Road, 10595-1530, Valhalla, NY, USA;Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China;School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China;The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China;

关键词: Gastric cancer;    D2 lymphadenectomy;    Lymph node dissection;    Gastrectomy;   

DOI  :  10.1186/s12957-017-1204-6

 received in 2016-11-08, accepted in 2017-07-08,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundGastric cancer remains a formidable treatment challenge. For decades, treatment consisted mostly of surgical intervention for this deadly disease. With improvements in the multi-disciplinary management of solid organ malignancies, the approach to this disease is being stepwise refined.Main bodyOne of the prevalent controversies in the surgical management of gastric cancer rests on the need for adequate harvesting of lymph nodes. For decades, lymph node dissection is regarded as a staging technique useful in only upstaging the disease. The adoption of D2 lymphadenectomy has been particularly slow to mature. But with prevailing data from Asia consistently demonstrating a survival benefit from lymphadenectomy, it calls into question the notion of lymphadenectomy as being solely a staging procedure.ConclusionsAs gastric resection techniques are being better defined in western countries and surgical morbidities lowered on its execution, D2 lymphadenectomy is becoming more accepted as the new standard in the management of gastric cancer.

【 授权许可】

CC BY   
© The Author(s). 2017