Assessment of troglitazone induced liver toxicity in a dynamically perfused two-organ Micro-Bioreactor system

BMC Proceedings

Poster Presentation

Frank Sonntag¹  Mathias Busek¹  Udo Klotzbach¹  Alexandra Lorenz²  Eva-Maria Materne²  Uwe Marx²  Silke Hoffmann²  Ilka Wagner²  Caroline Frädrich²  Roland Lauster²  Sven Brincker²  Reyk Horland² 

[1] Fraunhofer IWS Dresden, Winterbergstraße 28, 01277, Dresden, Germany;TU Berlin, Institute for Biotechnology, Faculty of Process Science and Engineering, Gustav-Meyer-Allee 25, 13355, Berlin, Germany;

关键词: Hepatic Stellate Cell;    Troglitazone;    Drug Induce Liver Injury;    Skin Equivalent;    Media Supernatant;   

DOI  :  10.1186/1753-6561-7-S6-P71

来源: Springer

【 授权许可】

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© Materne et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.