Presumptive myocarditis with ST-Elevation myocardial infarction presentation in young males as a new syndrome. Clinical significance and long term follow up

Cardiovascular Ultrasound

Research

Giuseppe Oreto¹  Alberto Albanese¹  Eugenio Picano²  Cristina Tritto³  Anna Ranieri³  Giovanni De Fabrizio³  Antonio Lauretti³  Claudio Fachechi³  Sergio Capone³  iovanni Sticchi³  Realino Renna³  Antonio Montinaro³  Marcello Costantini⁴ 

[1] Dipartimento di Medicina e Farmacologia, Università di Messina, Messina, Italy;Istituto di Fisiologia Clinica del CNR -Sezioni di Lecce e Pisa, Italy;Struttura Complessa di Cardiologia, Ospedale Santa Caterina Novella, Galatina, Italy;Struttura Complessa di Cardiologia, Ospedale Santa Caterina Novella, Galatina, Italy;Istituto di Fisiologia Clinica del CNR -Sezioni di Lecce e Pisa, Italy;

关键词: Acute Coronary Syndrome;    Myocarditis;    Normal Coronary Artery;    Acute Myocarditis;    Normal Coronary Angiogram;   

DOI  :  10.1186/1476-7120-9-1

 received in 2010-07-14, accepted in 2011-01-18,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundAcute myocarditis may mimic myocardial infarction, since affected patients complain of "typical" chest pain, the ECG changes are identical to those observed in acute coronary syndromes, and serum markers are increased. We describe a case series of presumptive myocarditis with ST segment elevation on admission ECG.Methods and ResultsFrom 1998 to 2009, 21 patients (20 males; age 17-42 years) were admitted with chest pain, persistent ST segment elevation, serum enzyme and troponine release. All but one patients had fever and flu-like symptoms prior to admission. No abnormal Q wave appeared in any ECG tracing, and angiography did not show significant coronary artery disease. Patients remained asymptomatic at long term follow-up, except 2 who experienced a late relapse, with the same clinical, electrocardiographic and serum findings as in the first clinical presentation.ConclusionPresumptive myocarditis of possible viral origin characterized by ST elevation mimicking myocardial infarction, good short term prognosis and some risk for recurrence is relatively frequent in young males and appears as a distinct clinical condition.

【 授权许可】

CC BY   
© Costantini et al; licensee BioMed Central Ltd. 2011