Left ventricular torsion shear angle volume analysis in patients with hypertension: a global approach for LV diastolic function

Journal of Cardiovascular Magnetic Resonance

Research

Chun G Schiros¹  Ravi V Desai¹ 

[1] Division of Cardiovascular Medicine, Department of Medicine, University of Alabama, BDB 101, CVMRI, 1530 3rd Ave South, 35294-0012, Birmingham, AL, USA;

关键词: Torsion hysteresis area;    loop;    Diastolic function;    Cardiovascular magnetic resonance;   

DOI  :  10.1186/s12968-014-0070-4

 received in 2014-01-23, accepted in 2014-08-13,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundTorsion shear angle φ is an important measure of left ventricular (LV) systolic and diastolic functions. Here we provide a novel index utilizing LV normalized torsion shear angle φ^ volume V^ loop to assess LV diastolic functional properties. We defined the area within φ^V^ loop as torsion hysteresis area, and hypothesized that it may be an important global parameter of diastolic function. We evaluated the φ^ changes to increased V^ during early diastole −dφ^/dV^ as a potential measure of LV suction.MethodsSixty resistant hypertension patients (HTN), forty control volunteers were studied using cardiovascular magnetic resonance with tissue tagging. Volumetric and torsional parameters were evaluated.ResultsHTN demonstrated concentric remodeling with preserved ejection fraction. HTN had significantly decreased normalized early filling rate, early diastolic mitral annulus velocity and E/A (1.33 ± 1.13 vs. 2.19 ± 1.07, P < 0.0001) vs. control. Torsion hysteresis area was greater (0.11 ± 0.07 vs. 0.079 ± 0.045, P < 0.001) and peak −dφ^/dV^ at early diastole was higher (10.46 ± 8.51 vs. 6.29 ± 3.85, P = 0.002) than control. Torsion hysteresis area was significantly correlated with E/A (r = −0.23, P = 0.025). Thirteen HTN patients had both E/A ratio < 1.12 (Control mean E/A-1SD) and torsion hysteresis area > 0.12 (Control mean torsion hysteresis area + 1SD).ConclusionsTorsion hysteresis area and peak early diastolic −dφ^/dV^ were significantly increased in hypertensive concentric remodeling. The φ^V^ loop takes into account the active and passive recoil processes of LV diastolic and systolic phases, therefore provides a new global description of LV diastolic function.

【 授权许可】

Unknown   
© Schiros et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.