Progress in lactic acid bacterial phage research

Microbial Cell Factories

Proceedings

Francesca Bottacini¹  Jennifer Mahony²  Gerald F Fitzgerald³  Douwe van Sinderen³ 

[1] >Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland;School of Microbiology, University College Cork, Cork, Ireland;School of Microbiology, University College Cork, Cork, Ireland;>Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland;

关键词: Bacteriophage;    dairy fermentation;    Antimicrobial;    Genome sequencing;   

DOI  :  10.1186/1475-2859-13-S1-S1

来源: Springer

【 摘 要 】

Research on lactic acid bacteria (LAB) has advanced significantly over the past number of decades and these developments have been driven by the parallel advances in technologies such as genomics, bioinformatics, protein expression systems and structural biology, combined with the ever increasing commercial relevance of this group of microorganisms. Some of the more significant and impressive outputs have been in the domain of bacteriophage-host interactions which provides a prime example of the cutting-edge model systems represented by LAB research. Here, we present a retrospective overview of the key advances in LAB phage research including phage-host interactions and co-evolution. We describe how in many instances this knowledge can be pivotal in creating real improvements in the application of LAB cultures in commercial practice.

【 授权许可】

Unknown   
© Mahony et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.