The association of metabolic syndrome and its factors with gallstone disease

BMC Family Practice

Research Article

Jenn-Chang Liou¹  Ying-Li Lin²  Yu-Wen Yang²  Chih-Hsiang Chiang²  I-Ching Lin³  Mei-Feng Wu⁴  Yi-Hui Yeh⁵ 

[1] Department of Healthcare Administration, Asia University, Taichung City, Taiwan;Family Medicine Department, Changhua Christian Hospital, No. 135, St. Nan-Xiao, 500, Changhua City, Taiwan;Family Medicine Department, Changhua Christian Hospital, No. 135, St. Nan-Xiao, 500, Changhua City, Taiwan;Department of Healthcare Administration, Asia University, Taichung City, Taiwan;School of Medicine, Chung Shan Medical University, Taichung City, Taiwan;Health Examination Department, Changhua Christian Hospital, Changhua City, Taiwan;Institute of Statistics, National Chung Hsing University, Taichung City, Taiwan;

关键词: Obesity;    Dyslipidemia;    Metabolic factors;    Metabolic syndrome;    Gallstone disease;   

DOI  :  10.1186/1471-2296-15-138

 received in 2014-05-08, accepted in 2014-07-18,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundTo investigate the association between metabolic syndrome, including its factors, and gallstone disease (GSD) in a Taiwanese population.MethodsWe conducted a cross-sectional study during 2011 ~ 2012. A total of 12050 subjects who completed a questionnaire and underwent physical examination, laboratory tests and abdominal ultrasonography formed the study population.ResultsThe prevalences of metabolic syndrome and gallstone disease were 24.09% and 6.16%. In an age- and sex-adjusted logistic regression model, metabolic syndrome was associated with gallstone disease (OR = 1.61; P < 0.0001). Age, abdominal obesity, and lower high-density lipoprotein cholesterol were associated with gallstone disease after adjusting for other factors. Females had a higher odds ratio than males in waist circumference for GSD, whereas males had a lower odds ratio than females in HDL-C for GSD.ConclusionsThe present study suggests that metabolic syndrome is related to gallstone disease. Waist circumference and high-density lipoprotein cholesterol are all associated with GSD. Men and women may possibly have different priorities and strategies to reduce the burden of GSD.

【 授权许可】

Unknown   
© Lin et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.