The nature, scope and impact of genomic prediction in beef cattle in the United States

Genetics Selection Evolution

Review

Dorian J Garrick¹ 

[1] Department of Animal Science, Iowa State University, 50011-3150, Ames, IA, USA;Institute of Veterinary, Animal & Biomedical Sciences, Massey University, Palmerston North, New Zealand;

关键词: Quantitative Trait Locus;    Single Nucleotide Polymorphism;    Beef Cattle;    Genomic Prediction;    Estimate Breeding Value;   

DOI  :  10.1186/1297-9686-43-17

 received in 2010-11-29, accepted in 2011-05-15,  发布年份 2011

来源: Springer

【 摘 要 】

Artificial selection has proven to be effective at altering the performance of animal production systems. Nevertheless, selection based on assessment of the genetic superiority of candidates is suboptimal as a result of errors in the prediction of genetic merit. Conventional breeding programs may extend phenotypic measurements on selection candidates to include correlated indicator traits, or delay selection decisions well beyond puberty so that phenotypic performance can be observed on progeny or other relatives. Extending the generation interval to increase the accuracy of selection reduces annual rates of gain compared to accurate selection and use of parents of the next generation at the immediate time they reach breeding age. Genomic prediction aims at reducing prediction errors at breeding age by exploiting information on the transmission of chromosome fragments from parents to selection candidates, in conjunction with knowledge on the value of every chromosome fragment. For genomic prediction to influence beef cattle breeding programs and the rate or cost of genetic gains, training analyses must be undertaken, and genomic prediction tools made available for breeders and other industry stakeholders. This paper reviews the nature or kind of studies currently underway, the scope or extent of some of those studies, and comments on the likely predictive value of genomic information for beef cattle improvement.

【 授权许可】

CC BY   
© Garrick; licensee BioMed Central Ltd. 2011