Comparison of hemodynamic, biochemical and hematological parameters of healthy pregnant women in the third trimester of pregnancy and the active labor phase

BMC Pregnancy and Childbirth

Research Article

Ana Flisser¹  Angélica Olivo-Díaz²  Simón Kawa-Karasik²  Norberto Reyes-Paredes²  Joel Martínez-Ocaña²  Luis Villanueva-Egan³  Fernando Rodríguez-Dennen⁴ 

[1] Facultad de Medicina, Universidad Nacional Autónoma de México, 04510, México, DF, Mexico;Hospital General "Dr. Manuel Gea González", Calzada de Tlalpan 4800, 14080, México, DF, Mexico;Hospital de la Mujer, Prol, Salvador Díaz Mirón 374, 11340, México, DF, Mexico;Instituto de Oftalmología Fundación Conde de Valenciana, Chimalpopoca 14 Colonia Obrera, C.P. 06800, DF, Mexico;

关键词: Preeclampsia;    Total Lung Capacity;    HELLP Syndrome;    Healthy Pregnant Woman;    Mexican Woman;   

DOI  :  10.1186/1471-2393-11-33

 received in 2010-12-03, accepted in 2011-05-06,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundPregnancy is accompanied by several hemodynamic, biochemical and hematological changes which revert to normal values after labor. The mean values of these parameters have been reported for developed countries, but not for Mexican women. Furthermore, labor constitutes a stress situation, in which these factors may be altered. It is known that serologic increase of heat shock protein (Hsp) 70 is associated with abnormal pregnancies, presenting very low level in normal pregnant women. Nevertheless, there are no studies where these measurements are compared in healthy pregnant women at their third trimester of pregnancy (3TP) and the active labor phase (ActLP).MethodsSeventy five healthy Mexican pregnant women were included. Hemodynamic, biochemical and hematological parameters were obtained in all cases, and serum Hsp70 levels were measured in a sample of 15 women at 3TP and at ActLP.ResultsSignificant differences were found in most analysis performed and in Hsp70 concentration at 3TP as compared to ActLP, however all were within normal range in both conditions, supporting that only in pathological pregnancies Hsp70 is drastically increased.ConclusionResults obtained indicate that 3TP and ActLP have clinical similarities in normal pregnancies, therefore if abnormalities are found during 3TP, precautions should be taken before ActLP.

【 授权许可】

Unknown   
© Rodríguez-Dennen et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.