Metagenomic analysis of gut microbiome and resistome of Whooper and Black Swans: a one health perspective

BMC Genomics

Research

Junqiang Li¹  Kaihui Zhang¹  Huiyan Xu¹  Yilin Wang¹  Xiaoying Li¹  Ziyang Qin¹  Longxian Zhang¹  Yin Fu¹  Fa Shan² 

[1] College of Veterinary Medicine, Henan Agricultural University, No. 15 Longzihu University Area, Zhengzhou New District, 450046, Zhengzhou, China;International Joint Research Laboratory for Zoonotic Diseases of Henan, 450046, Zhengzhou, China;Ministry of Agriculture and Rural Areas Key Laboratory for Quality and Safety Control of Poultry Products, 450046, Zhengzhou, China;College of Veterinary Medicine, Northwest A&F University, 712100, Yangling, China;

关键词: Whooper swan;    Black swan;    Microbiome;    Resistome;   

DOI  :  10.1186/s12864-023-09742-2

 received in 2022-12-07, accepted in 2023-10-13,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundWith the promotion of “One Health,” the health of animals and their impact on the environment have become major concerns recently. Widely distributed in China, the whooper swans (Cygnus cygnus) and black swans (Cygnus atratus) are not only important to the ecological environment, but they may also potentially influence public health security. The metagenomic approach was adopted to uncover the impacts of the gut microbiota of swans on host and public health.ResultsIn this study, the intestinal microbiome and resistome of migratory whooper swans and captive-bred black swans were identified. The results revealed similar gut microbes and functional compositions in whooper and black swans. Interestingly, different bacteria and probiotics were enriched by overwintering whooper swans. We also found that Acinetobacter and Escherichia were significantly enriched in early wintering period swans and that clinically important pathogens were more abundant in black swans. Whooper swans and black swans are potential reservoirs of antibiotic resistance genes (ARGs) and novel ARGs, and the abundance of novel ARGs in whooper swans was significantly higher than that in black swans. Metagenomic assembly–based host tracking revealed that most ARG-carrying contigs originated from Proteobacteria (mainly Gammaproteobacteria).ConclusionsThe results revealed spatiotemporal changes in microbiome and resistome in swans, providing a reference for safeguarding public health security and preventing animal epidemics.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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